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Nexavar in breast cancer

Study record managers: refer to the Data Element Definitions if submitting registration or results information. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
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Nexavar Slows the Progression of Breast Cancer

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Nexavar Slows the Progression of Breast Cancer

Study record managers: refer to the Data Element Definitions if submitting registration or results information. Drugs used in chemotherapy, such as paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving sorafenib together with paclitaxel may kill more tumor cells. PURPOSE: This phase II trial is studying the side effects of giving sorafenib together with paclitaxel and to how well it works in treating patients with metastatic breast cancer. Patients receive oral sorafenib tosylate twice daily on days and paclitaxel IV over 1 hour on days 1, 8, and
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Sorafenib in breast cancer treatment: A systematic review and overview of clinical trials.

Sometimes hormone-receptor-positive breast cancer comes back or grows during treatment with hormonal therapy. Abnormal genes give breast cancer cells the ability to grow, divide, and spread uncontrollably. The abnormal genes that make cells cancerous also make them more likely to have still more abnormal genetic changes. This partly explains why breast cancer treatments stop working and why everyone doesn't get the same benefits from a treatment. In this study, the cancer cells changed so they weren't affected by hormones, so that reducing the amount of hormones or blocking their effects with hormonal therapy wouldn't work anymore.
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Nexavar Sorafenib. Sorafenib - Substance Summary. Sorafenib Nexavar. Toggle navigation.

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